AustralieFrV1, Main, Exploration, bibRecord, 006760

Regional differences in treatment for osteoporosis. The Global Longitudinal Study of Osteoporosis in Women (GLOW)

Identifieur interne : 006760 ( Main/Exploration ); précédent : 006759; suivant : 006761

Regional differences in treatment for osteoporosis. The Global Longitudinal Study of Osteoporosis in Women (GLOW)

Auteurs : Adolfo Diez-Perez [Espagne] ; Frederick H. Hooven [États-Unis] ; Jonathan D. Adachi [Canada] ; Silvano Adami [Italie] ; Frederick A. Anderson [États-Unis] ; Steven Boonen [Belgique] ; Roland Chapurlat [France] ; Juliet E. Compston [Royaume-Uni] ; Cyrus Cooper [Royaume-Uni] ; Pierre Delmas [France] ; Susan L. Greenspan [États-Unis] ; Andrea Z. Lacroix [États-Unis] ; Robert Lindsay [États-Unis] ; J. Coen Netelenbos [Pays-Bas] ; Johannes Pfeilschifter [Allemagne] ; Christian Roux [France] ; Kenneth G. Saag [États-Unis] ; Philip Sambrook [Australie] ; Stuart Silverman [États-Unis] ; Ethel S. Siris [États-Unis] ; Nelson B. Watts [États-Unis] ; Grigor Nika [États-Unis] ; Stephen H. Gehlbach [États-Unis]

Source :

Bone : (New York, NY) [ 8756-3282 ] ; 2011.

RBID : Pascal:12-0170990

Descripteurs français

Pascal (Inist)
- Traitement régional, Ostéoporose, Femme, Fracture, Facteur risque, Prévention, Morphologie.
Wicri :
- topic : Femme.

English descriptors

KwdEn :
- Fracture, Morphology, Osteoporosis, Prevention, Regional treatment, Risk factor, Woman.

Abstract

Purpose: To determine if important geographic differences exist in treatment rates for osteoporosis and whether this variation can be explained by regional variation in risk factors. Methods: The Global Longitudinal Study of Osteoporosis in Women is an observational study of women ≥55 years sampled from primary care practices in 10 countries. Self-administered questionnaires were used to collect data on patient characteristics, risk factors for fracture, previous fractures, anti-osteoporosis medication, and health status. Results: Among 58,009 women, current anti-osteoporosis medication use was lowest in Northern Europe (16%) and highest in USA and Australia (32%). Between 48% (USA, Southern Europe) and 68% (Northern Europe) of women aged ≥65 years with a history of spine or hip fracture since age 45 were untreated. Among women with osteoporosis, the percentage of treated cases was lowest in Europe (45-52% versus 62-65% elsewhere). Women with osteopenia and no other risk factors were treated with anti-osteoporosis medication most frequently in USA (31%) and Canada (31%), and least frequently in Southern Europe (12%), Northern Europe (13%), and Australia (16%). After adjusting for risk factors, US women were threefold as likely to be treated with anti-osteoporosis medication as Northern European women (odds ratio 2.8; 95% confidence interval 2.5-3.1 ) and 1.5 times as likely to be treated as Southern European women (1.5, 1.4-1.6). Up to half of women reporting previous hip or spine fracture did not receive treatment. Conclusions: The likelihood of being treated for osteoporosis differed between regions, and cannot be explained by variation in risk factors. Many women at risk of fracture do not receive prophylaxis.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897770

Affiliations:

Le document en format XML

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<author><name sortKey="Compston, Juliet E" sort="Compston, Juliet E" uniqKey="Compston J" first="Juliet E." last="Compston">Juliet E. Compston</name>
<affiliation wicri:level="1"><inist:fA14 i1="07"><s1>University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital</s1>
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<sZ>8 aut.</sZ>
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<country>Royaume-Uni</country>
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</affiliation>
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<author><name sortKey="Cooper, Cyrus" sort="Cooper, Cyrus" uniqKey="Cooper C" first="Cyrus" last="Cooper">Cyrus Cooper</name>
<affiliation wicri:level="3"><inist:fA14 i1="08"><s1>MRC Epidemiology Resource Centre, University of Southampton, Southampton General Hospital and Norman Collisson Chair of Musculoskeletal Sciences, University of Oxford</s1>
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<s3>GBR</s3>
<sZ>9 aut.</sZ>
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<country>Royaume-Uni</country>
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<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Delmas, Pierre" sort="Delmas, Pierre" uniqKey="Delmas P" first="Pierre" last="Delmas">Pierre Delmas</name>
<affiliation wicri:level="3"><inist:fA14 i1="09"><s1>Hôpital Edouard Herriot</s1>
<s2>Lyon</s2>
<s3>FRA</s3>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
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<s3>USA</s3>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><settlement type="city">Pittsburgh</settlement>
<region type="state">Pennsylvanie</region>
</placeName>
<orgName type="university">Université de Pittsburgh</orgName>
</affiliation>
</author>
<author><name sortKey="Lacroix, Andrea Z" sort="Lacroix, Andrea Z" uniqKey="Lacroix A" first="Andrea Z." last="Lacroix">Andrea Z. Lacroix</name>
<affiliation wicri:level="1"><inist:fA14 i1="11"><s1>Fred Hutchinson Cancer Research Center</s1>
<s2>Seattle, WA</s2>
<s3>USA</s3>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Fred Hutchinson Cancer Research Center</wicri:noRegion>
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</author>
<author><name sortKey="Lindsay, Robert" sort="Lindsay, Robert" uniqKey="Lindsay R" first="Robert" last="Lindsay">Robert Lindsay</name>
<affiliation wicri:level="1"><inist:fA14 i1="12"><s1>Regional Bone Center, Helen Hayes Hospital</s1>
<s2>West Haverstraw, NY</s2>
<s3>USA</s3>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>West Haverstraw, NY</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Coen Netelenbos, J" sort="Coen Netelenbos, J" uniqKey="Coen Netelenbos J" first="J." last="Coen Netelenbos">J. Coen Netelenbos</name>
<affiliation wicri:level="3"><inist:fA14 i1="13"><s1>Department of Endocrinology, VU University Medical Center</s1>
<s2>Amsterdam</s2>
<s3>NLD</s3>
<sZ>14 aut.</sZ>
</inist:fA14>
<country>Pays-Bas</country>
<placeName><settlement type="city">Amsterdam</settlement>
<region nuts="2" type="province">Hollande-Septentrionale</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Pfeilschifter, Johannes" sort="Pfeilschifter, Johannes" uniqKey="Pfeilschifter J" first="Johannes" last="Pfeilschifter">Johannes Pfeilschifter</name>
<affiliation wicri:level="1"><inist:fA14 i1="14"><s1>Alfried Krupp Krankenhaus, Department of Internal Medicine III</s1>
<s2>Essen</s2>
<s3>DEU</s3>
<sZ>15 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<wicri:noRegion>Essen</wicri:noRegion>
<wicri:noRegion>Department of Internal Medicine III</wicri:noRegion>
<wicri:noRegion>Essen</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Roux, Christian" sort="Roux, Christian" uniqKey="Roux C" first="Christian" last="Roux">Christian Roux</name>
<affiliation wicri:level="3"><inist:fA14 i1="15"><s1>Paris Descartes University, Cochin Hospital</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Saag, Kenneth G" sort="Saag, Kenneth G" uniqKey="Saag K" first="Kenneth G." last="Saag">Kenneth G. Saag</name>
<affiliation wicri:level="1"><inist:fA14 i1="16"><s1>University of Alabama-Birmingham, Division of Clinical Immunology and Rheumatology</s1>
<s2>Birmingham, AL</s2>
<s3>USA</s3>
<sZ>17 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Birmingham, AL</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sambrook, Philip" sort="Sambrook, Philip" uniqKey="Sambrook P" first="Philip" last="Sambrook">Philip Sambrook</name>
<affiliation wicri:level="1"><inist:fA14 i1="17"><s1>University of Sydney-Royal North Shore Hospital, St. Leonards</s1>
<s2>Sydney, NSW</s2>
<s3>AUS</s3>
<sZ>18 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<wicri:noRegion>Sydney, NSW</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Silverman, Stuart" sort="Silverman, Stuart" uniqKey="Silverman S" first="Stuart" last="Silverman">Stuart Silverman</name>
<affiliation wicri:level="1"><inist:fA14 i1="18"><s1>Cedars-Sinai Medical Center</s1>
<s2>Los Angeles, CA</s2>
<s3>USA</s3>
<sZ>19 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Cedars-Sinai Medical Center</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Siris, Ethel S" sort="Siris, Ethel S" uniqKey="Siris E" first="Ethel S." last="Siris">Ethel S. Siris</name>
<affiliation wicri:level="1"><inist:fA14 i1="19"><s1>Columbia University Medical Center</s1>
<s2>New York, NY</s2>
<s3>USA</s3>
<sZ>20 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Columbia University Medical Center</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Watts, Nelson B" sort="Watts, Nelson B" uniqKey="Watts N" first="Nelson B." last="Watts">Nelson B. Watts</name>
<affiliation wicri:level="1"><inist:fA14 i1="20"><s1>Bone Health and Osteoporosis Center, University of Cincinnati</s1>
<s2>Cincinnati, OH</s2>
<s3>USA</s3>
<sZ>21 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Cincinnati, OH</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Nika, Grigor" sort="Nika, Grigor" uniqKey="Nika G" first="Grigor" last="Nika">Grigor Nika</name>
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<sZ>2 aut.</sZ>
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<sZ>22 aut.</sZ>
<sZ>23 aut.</sZ>
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<country>États-Unis</country>
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</author>
<author><name sortKey="Gehlbach, Stephen H" sort="Gehlbach, Stephen H" uniqKey="Gehlbach S" first="Stephen H." last="Gehlbach">Stephen H. Gehlbach</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Center for Outcomes Research, University of Massachusetts Medical School</s1>
<s2>Worcester, MA</s2>
<s3>USA</s3>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>22 aut.</sZ>
<sZ>23 aut.</sZ>
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<country>États-Unis</country>
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<series><title level="j" type="main">Bone : (New York, NY)</title>
<title level="j" type="abbreviated">Bone : (NY NY)</title>
<idno type="ISSN">8756-3282</idno>
<imprint><date when="2011">2011</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Bone : (New York, NY)</title>
<title level="j" type="abbreviated">Bone : (NY NY)</title>
<idno type="ISSN">8756-3282</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Fracture</term>
<term>Morphology</term>
<term>Osteoporosis</term>
<term>Prevention</term>
<term>Regional treatment</term>
<term>Risk factor</term>
<term>Woman</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Traitement régional</term>
<term>Ostéoporose</term>
<term>Femme</term>
<term>Fracture</term>
<term>Facteur risque</term>
<term>Prévention</term>
<term>Morphologie</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Femme</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Purpose: To determine if important geographic differences exist in treatment rates for osteoporosis and whether this variation can be explained by regional variation in risk factors. Methods: The Global Longitudinal Study of Osteoporosis in Women is an observational study of women ≥55 years sampled from primary care practices in 10 countries. Self-administered questionnaires were used to collect data on patient characteristics, risk factors for fracture, previous fractures, anti-osteoporosis medication, and health status. Results: Among 58,009 women, current anti-osteoporosis medication use was lowest in Northern Europe (16%) and highest in USA and Australia (32%). Between 48% (USA, Southern Europe) and 68% (Northern Europe) of women aged ≥65 years with a history of spine or hip fracture since age 45 were untreated. Among women with osteoporosis, the percentage of treated cases was lowest in Europe (45-52% versus 62-65% elsewhere). Women with osteopenia and no other risk factors were treated with anti-osteoporosis medication most frequently in USA (31%) and Canada (31%), and least frequently in Southern Europe (12%), Northern Europe (13%), and Australia (16%). After adjusting for risk factors, US women were threefold as likely to be treated with anti-osteoporosis medication as Northern European women (odds ratio 2.8; 95% confidence interval 2.5-3.1 ) and 1.5 times as likely to be treated as Southern European women (1.5, 1.4-1.6). Up to half of women reporting previous hip or spine fracture did not receive treatment. Conclusions: The likelihood of being treated for osteoporosis differed between regions, and cannot be explained by variation in risk factors. Many women at risk of fracture do not receive prophylaxis.</div>
</front>
</TEI>
<affiliations><list><country><li>Allemagne</li>
<li>Australie</li>
<li>Belgique</li>
<li>Canada</li>
<li>Espagne</li>
<li>France</li>
<li>Italie</li>
<li>Pays-Bas</li>
<li>Royaume-Uni</li>
<li>États-Unis</li>
</country>
<region><li>Angleterre</li>
<li>Auvergne-Rhône-Alpes</li>
<li>Catalogne</li>
<li>Hollande-Septentrionale</li>
<li>Ontario</li>
<li>Oxfordshire</li>
<li>Pennsylvanie</li>
<li>Province du Brabant flamand</li>
<li>Rhône-Alpes</li>
<li>Région flamande</li>
<li>Île-de-France</li>
</region>
<settlement><li>Amsterdam</li>
<li>Barcelone</li>
<li>Hamilton (Ontario)</li>
<li>Louvain</li>
<li>Lyon</li>
<li>Oxford</li>
<li>Paris</li>
<li>Pittsburgh</li>
</settlement>
<orgName><li>Katholieke Universiteit Leuven</li>
<li>Université McMaster</li>
<li>Université de Pittsburgh</li>
</orgName>
</list>
<tree><country name="Espagne"><region name="Catalogne"><name sortKey="Diez Perez, Adolfo" sort="Diez Perez, Adolfo" uniqKey="Diez Perez A" first="Adolfo" last="Diez-Perez">Adolfo Diez-Perez</name>
</region>
</country>
<country name="États-Unis"><noRegion><name sortKey="Hooven, Frederick H" sort="Hooven, Frederick H" uniqKey="Hooven F" first="Frederick H." last="Hooven">Frederick H. Hooven</name>
</noRegion>
<name sortKey="Anderson, Frederick A" sort="Anderson, Frederick A" uniqKey="Anderson F" first="Frederick A." last="Anderson">Frederick A. Anderson</name>
<name sortKey="Gehlbach, Stephen H" sort="Gehlbach, Stephen H" uniqKey="Gehlbach S" first="Stephen H." last="Gehlbach">Stephen H. Gehlbach</name>
<name sortKey="Greenspan, Susan L" sort="Greenspan, Susan L" uniqKey="Greenspan S" first="Susan L." last="Greenspan">Susan L. Greenspan</name>
<name sortKey="Lacroix, Andrea Z" sort="Lacroix, Andrea Z" uniqKey="Lacroix A" first="Andrea Z." last="Lacroix">Andrea Z. Lacroix</name>
<name sortKey="Lindsay, Robert" sort="Lindsay, Robert" uniqKey="Lindsay R" first="Robert" last="Lindsay">Robert Lindsay</name>
<name sortKey="Nika, Grigor" sort="Nika, Grigor" uniqKey="Nika G" first="Grigor" last="Nika">Grigor Nika</name>
<name sortKey="Saag, Kenneth G" sort="Saag, Kenneth G" uniqKey="Saag K" first="Kenneth G." last="Saag">Kenneth G. Saag</name>
<name sortKey="Silverman, Stuart" sort="Silverman, Stuart" uniqKey="Silverman S" first="Stuart" last="Silverman">Stuart Silverman</name>
<name sortKey="Siris, Ethel S" sort="Siris, Ethel S" uniqKey="Siris E" first="Ethel S." last="Siris">Ethel S. Siris</name>
<name sortKey="Watts, Nelson B" sort="Watts, Nelson B" uniqKey="Watts N" first="Nelson B." last="Watts">Nelson B. Watts</name>
</country>
<country name="Canada"><region name="Ontario"><name sortKey="Adachi, Jonathan D" sort="Adachi, Jonathan D" uniqKey="Adachi J" first="Jonathan D." last="Adachi">Jonathan D. Adachi</name>
</region>
</country>
<country name="Italie"><noRegion><name sortKey="Adami, Silvano" sort="Adami, Silvano" uniqKey="Adami S" first="Silvano" last="Adami">Silvano Adami</name>
</noRegion>
</country>
<country name="Belgique"><region name="Région flamande"><name sortKey="Boonen, Steven" sort="Boonen, Steven" uniqKey="Boonen S" first="Steven" last="Boonen">Steven Boonen</name>
</region>
</country>
<country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Chapurlat, Roland" sort="Chapurlat, Roland" uniqKey="Chapurlat R" first="Roland" last="Chapurlat">Roland Chapurlat</name>
</region>
<name sortKey="Delmas, Pierre" sort="Delmas, Pierre" uniqKey="Delmas P" first="Pierre" last="Delmas">Pierre Delmas</name>
<name sortKey="Roux, Christian" sort="Roux, Christian" uniqKey="Roux C" first="Christian" last="Roux">Christian Roux</name>
</country>
<country name="Royaume-Uni"><noRegion><name sortKey="Compston, Juliet E" sort="Compston, Juliet E" uniqKey="Compston J" first="Juliet E." last="Compston">Juliet E. Compston</name>
</noRegion>
<name sortKey="Cooper, Cyrus" sort="Cooper, Cyrus" uniqKey="Cooper C" first="Cyrus" last="Cooper">Cyrus Cooper</name>
</country>
<country name="Pays-Bas"><region name="Hollande-Septentrionale"><name sortKey="Coen Netelenbos, J" sort="Coen Netelenbos, J" uniqKey="Coen Netelenbos J" first="J." last="Coen Netelenbos">J. Coen Netelenbos</name>
</region>
</country>
<country name="Allemagne"><noRegion><name sortKey="Pfeilschifter, Johannes" sort="Pfeilschifter, Johannes" uniqKey="Pfeilschifter J" first="Johannes" last="Pfeilschifter">Johannes Pfeilschifter</name>
</noRegion>
</country>
<country name="Australie"><noRegion><name sortKey="Sambrook, Philip" sort="Sambrook, Philip" uniqKey="Sambrook P" first="Philip" last="Sambrook">Philip Sambrook</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>

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Serveur d'exploration sur les relations entre la France et l'Australie

Regional differences in treatment for osteoporosis. The Global Longitudinal Study of Osteoporosis in Women (GLOW)

Regional differences in treatment for osteoporosis. The Global Longitudinal Study of Osteoporosis in Women (GLOW)

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	Serveur d'exploration sur les relations entre la France et l'Australie
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